{"id":12997,"date":"2021-04-12T11:04:45","date_gmt":"2021-04-12T11:04:45","guid":{"rendered":"https:\/\/birthhelp.in\/?page_id=12997"},"modified":"2024-05-10T09:47:55","modified_gmt":"2024-05-10T09:47:55","slug":"pre-implantation-genetic-testing","status":"publish","type":"page","link":"https:\/\/birthhelp.in\/pre-implantation-genetic-testing\/","title":{"rendered":"Pre Implantation Generic Testing(PGT)"},"content":{"rendered":"\t\t
This article offers a comprehensive insight into Preimplantation Genetic Testing tests available to fertility patients. We delve into PGT-A, PGT-M, and PGT-SR, aiming to boost IVF success rates at our esteemed IVF Fertility Hospital in Guntur<\/a><\/strong>.<\/span> Ensuring the transfer of only genetically healthy embryos is key to successful fertility treatment.<\/p> At Birth Help Center<\/b>, we provide comprehensive assisted fertility solutions starting right from initial consultations through IVF protocols involving genetic embryo assessments to successful implantation up to delivery and beyond. You can trust us to be your partners at each milestone.<\/p> PGT or preimplantation genetic testing enables specialized screening of embryos created through IVF<\/b> <\/a>procedures to detect potential genetic anomalies before transfer into the uterus. Selecting and transferring only healthy embryos verified to carry balanced, normal chromosomes increases the chances of successful implantation and live birth.<\/p> PGTA allows identifying embryos carrying an abnormal number of chromosomes in a condition called aneuploidy which is the leading cause of failed conceptions and recurrent pregnancy loss even in younger IVF patients. Testing via advanced NGS-based PGT-A minimizes such losses.<\/p> PGTA helps guide embryo selection to choose euploid ones in patients with advanced maternal age \u226535 years, a history of miscarriages or failed IVF cycles<\/b> indicating probable undiagnosed aneuploidy issues and severe male factor infertility among others. The test is conducted after retrieval before frozen embryo transfers.<\/p> PGTM enables the detection of single gene defects or mutations linked to over 200 hereditary disorders passed down genetically in families – like cystic fibrosis<\/b>, thalassemias<\/b>, Huntington’s disease<\/b> etc. By selecting and transferring only healthy embryos screened negative for the concerned familial disorder, affected parents have improved chances of having children free from the condition.<\/p> PGT-SR helps identify embryos having balanced translocations, inversions or other structural rearrangements which makes miscarriage almost a certainty. Skipping transfer of such abnormal embryos with extremely poor prognosis via comprehensive chromosomal assessment<\/b> prevents painful pregnancy losses later.<\/p> Preimplantation Genetic Testing (PGT) is a crucial component of the in vitro fertilization (IVF) process. It allows for the assessment of embryos to identify genetic abnormalities before they are transferred to the uterus.\u00a0<\/p> There are three main types of PGT, each serving a specific purpose:<\/i><\/p> Purpose: <\/strong>PGT-A screens embryos for aneuploidy, which refers to an abnormal number of chromosomes.<\/p> PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements):\u00a0<\/p> Purpose: <\/strong>PGT-SR detects structural abnormalities in chromosomes, such as translocations or inversions.<\/p> PGT-M (Preimplantation Genetic Testing for Monogenic Disorders):<\/p> Purpose: <\/strong>PGT-M focuses on specific single-gene disorders (monogenic disorders).<\/p> NGS Next Generation Sequencing Now Identifies Mosaicism in Embryos<\/p> IVF Fertility Hospital in Guntur <\/span>can<\/span>\u00a0leverage\u00a0advanced Next Generation Sequencing<\/b> (NGS) based PGT testing which can accurately identify mosaic embryos<\/i>.\u00a0 Having a mix of normal and abnormal cells, unlike traditional methods. This enables reliable differentiation between mosaics and uniformly euploid embryos for preferential transfer maximizing viability. Speak to our fertility specialists to learn more!<\/p> While ‘PGT testing’\u00a0<\/i>provides invaluable insights into embryo viability, uterine receptivity, and other factors, they also play a role. PGT cannot guarantee a successful pregnancy<\/u><\/i> <\/strong>but significantly improves odds when combined with high-quality lab procedures. Personalized approach unique to the IVF Fertility Hospital in Guntur<\/strong>!\u00a0Please call us to <\/span>schedule your first consultation<\/span><\/a>.<\/span><\/p> “Don’t let fertility challenges hold you back. Choose a Birth Help Center and open the door to a world of possibilities<\/strong><\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t <\/div>\r\n <\/div>\r\n <\/div>\r\n Fertility Through Delivery – IVF Fertility Hospital in Guntur is Here\u00a0<\/h2>
What is Preimplantation Genetic Testing (PGT) for Embryos?<\/h2>
Preimplantation Genetic Testing for Aneuploidy (PGTA)<\/h3>
Candidates for PGTA Testing\u00a0<\/h3>
Preimplantation Genetic Testing for Monogenic Disorders (PGTM)<\/h2>
PGT for Chromosomal Rearrangements (PGTSR)<\/h2>
How are PGTA, PGTSR and PGTM performed on Embryos during IVF?<\/h2>
PGT-A (Preimplantation Genetic Testing for Aneuploidy)<\/h3>
Process:<\/h4>
Process:<\/h4>
Process:<\/h4>
Embryo Preimplantation Genetic Testing Considerations<\/h3>
Services<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t